Blar i forfatter "Hellemo, Lars"

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    • Next frontiers in energy system modelling: A review on challenges and the state of the art 

      Fodstad, Marte; Crespo del Granado, Pedro; Hellemo, Lars; Knudsen, Brage Rugstad; Pisciella, Paolo; Silvast, Antti; Bordin, Chiara; Schmidt, Sarah; Straus, Julian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-26)
      Energy Systems Modelling is growing in relevance on providing insights and strategies to plan a carbon-neutral future. The implementation of an effective energy transition plan faces multiple challenges, spanning from the integration of the operations of different energy carriers and sectors to the consideration of multiple spatial and temporal resolutions. In this review, we outline these challenges ...

    • Patient-tailored levothyroxine dosage with pharmacokinetic/pharmacodynamic modeling: A novel approach after total thyroidectomy 

      Brun, Vegard Heimly; Eriksen, Amund H.; Selseth, Ruth; Johansson, Kenth; Vik, Renate; Davidsen, Benedicte; Kaut, Michal; Hellemo, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
      Background: After seven decades of levothyroxine (LT4) replacement therapy, dosage adjustment still takes several months. We have developed a decision aid tool (DAT) that models LT4 pharmacometrics and enables patient-tailored dosage. The aim of this was to speed up dosage adjustments for patients after total thyroidectomy.<p> <p>Methods: The DAT computer program was developed with a group of 46 ...